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Simultaneous targeting of androgen receptor (AR) and MAPK-interacting kinases (MNKs) by novel retinamides inhibits growth of human prostate cancer cell lines

Androgen receptor (AR) and MNK activated eIF4E signaling promotes the development and progression of prostate cancer (PCa). In this study, we report that our Novel Retinamides (NRs) target both AR signaling and eIF4E translation in androgen sensitive and castration resistant PCa cells via enhancing...

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Detalles Bibliográficos
Autores principales:	Ramamurthy, Vidya P., Ramalingam, Senthilmurugan, Gediya, Lalji, Kwegyir-Afful, Andrew K., Njar, Vincent C.O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2014
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413647/ https://www.ncbi.nlm.nih.gov/pubmed/25605250

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