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Misfolding, Aggregation, and Disordered Segments in c-Abl and p53 in Human Cancer

The current understanding of the molecular mechanisms that lead to cancer is not sufficient to explain the loss or gain of function in proteins related to tumorigenic processes. Among them, more than 100 oncogenes, 20–30 tumor-suppressor genes, and hundreds of genes participating in DNA repair and r...

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Detalles Bibliográficos
Autores principales:	de Oliveira, Guilherme A. P., Rangel, Luciana P., Costa, Danielly C., Silva, Jerson L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413674/ https://www.ncbi.nlm.nih.gov/pubmed/25973395 http://dx.doi.org/10.3389/fonc.2015.00097

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