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NAD(P)H-Independent Asymmetric C=C Bond Reduction Catalyzed by Ene Reductases by Using Artificial Co-substrates as the Hydrogen Donor

To develop a nicotinamide-independent single flavoenzyme system for the asymmetric bioreduction of C=C bonds, four types of hydrogen donor, encompassing more than 50 candidates, were investigated. Six highly potent, cheap, and commercially available co-substrates were identified that (under the opti...

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Detalles Bibliográficos
Autores principales:	Winkler, Christoph K, Clay, Dorina, Entner, Marcello, Plank, Markus, Faber, Kurt
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2014
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413776/ https://www.ncbi.nlm.nih.gov/pubmed/24382795 http://dx.doi.org/10.1002/chem.201303897

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