Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study

OBJECTIVE: To investigate the role of longitudinal plasma neurofilament heavy chain protein (NfH) levels as an indicator of clinical progression and survival in amyotrophic lateral sclerosis (ALS). METHODS: A cross-sectional study involving 136 clinically heterogeneous patients with ALS and 104 heal...

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Detalles Bibliográficos
Autores principales: Lu, Ching-Hua, Petzold, Axel, Topping, Jo, Allen, Kezia, Macdonald-Wallis, Corrie, Clarke, Jan, Pearce, Neil, Kuhle, Jens, Giovannoni, Gavin, Fratta, Pietro, Sidle, Katie, Fish, Mark, Orrell, Richard, Howard, Robin, Greensmith, Linda, Malaspina, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2015
Materias:
Neurodegeneration
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413806/
https://www.ncbi.nlm.nih.gov/pubmed/25009280
http://dx.doi.org/10.1136/jnnp-2014-307672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413806/
https://www.ncbi.nlm.nih.gov/pubmed/25009280
http://dx.doi.org/10.1136/jnnp-2014-307672

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