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A simple biophysical model emulates budding yeast chromosome condensation

Mitotic chromosomes were one of the first cell biological structures to be described, yet their molecular architecture remains poorly understood. We have devised a simple biophysical model of a 300 kb-long nucleosome chain, the size of a budding yeast chromosome, constrained by interactions between...

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Detalles Bibliográficos
Autores principales:	Cheng, Tammy MK, Heeger, Sebastian, Chaleil, Raphaël AG, Matthews, Nik, Stewart, Aengus, Wright, Jon, Lim, Carmay, Bates, Paul A, Uhlmann, Frank
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2015
Materias:	Computational and Systems Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413874/ https://www.ncbi.nlm.nih.gov/pubmed/25922992 http://dx.doi.org/10.7554/eLife.05565

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