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A Novel Brain Stimulation Technology Provides Compatibility with MRI

Clinical electrical stimulation systems — such as pacemakers and deep brain stimulators (DBS) — are an increasingly common therapeutic option to treat a large range of medical conditions. Despite their remarkable success, one of the significant limitations of these medical devices is the limited com...

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Autores principales: Serano, Peter, Angelone, Leonardo M., Katnani, Husam, Eskandar, Emad, Bonmassar, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413880/
https://www.ncbi.nlm.nih.gov/pubmed/25924189
http://dx.doi.org/10.1038/srep09805
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author Serano, Peter
Angelone, Leonardo M.
Katnani, Husam
Eskandar, Emad
Bonmassar, Giorgio
author_facet Serano, Peter
Angelone, Leonardo M.
Katnani, Husam
Eskandar, Emad
Bonmassar, Giorgio
author_sort Serano, Peter
collection PubMed
description Clinical electrical stimulation systems — such as pacemakers and deep brain stimulators (DBS) — are an increasingly common therapeutic option to treat a large range of medical conditions. Despite their remarkable success, one of the significant limitations of these medical devices is the limited compatibility with magnetic resonance imaging (MRI), a standard diagnostic tool in medicine. During an MRI exam, the leads used with these devices, implanted in the body of the patient, act as an electric antenna potentially causing a large amount of energy to be absorbed in the tissue, which can lead to serious heat-related injury. This study presents a novel lead design that reduces the antenna effect and allows for decreased tissue heating during MRI. The optimal parameters of the wire design were determined by a combination of computational modeling and experimental measurements. The results of these simulations were used to build a prototype, which was tested in a gel phantom during an MRI scan. Measurement results showed a three-fold decrease in heating when compared to a commercially available DBS lead. Accordingly, the proposed design may allow a significantly increased number of patients with medical implants to have safe access to the diagnostic benefits of MRI.
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spelling pubmed-44138802015-05-08 A Novel Brain Stimulation Technology Provides Compatibility with MRI Serano, Peter Angelone, Leonardo M. Katnani, Husam Eskandar, Emad Bonmassar, Giorgio Sci Rep Article Clinical electrical stimulation systems — such as pacemakers and deep brain stimulators (DBS) — are an increasingly common therapeutic option to treat a large range of medical conditions. Despite their remarkable success, one of the significant limitations of these medical devices is the limited compatibility with magnetic resonance imaging (MRI), a standard diagnostic tool in medicine. During an MRI exam, the leads used with these devices, implanted in the body of the patient, act as an electric antenna potentially causing a large amount of energy to be absorbed in the tissue, which can lead to serious heat-related injury. This study presents a novel lead design that reduces the antenna effect and allows for decreased tissue heating during MRI. The optimal parameters of the wire design were determined by a combination of computational modeling and experimental measurements. The results of these simulations were used to build a prototype, which was tested in a gel phantom during an MRI scan. Measurement results showed a three-fold decrease in heating when compared to a commercially available DBS lead. Accordingly, the proposed design may allow a significantly increased number of patients with medical implants to have safe access to the diagnostic benefits of MRI. Nature Publishing Group 2015-04-29 /pmc/articles/PMC4413880/ /pubmed/25924189 http://dx.doi.org/10.1038/srep09805 Text en Copyright © 2015, Macmillan Publishers Limited. All rights reserved http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article's Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder in order to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Serano, Peter
Angelone, Leonardo M.
Katnani, Husam
Eskandar, Emad
Bonmassar, Giorgio
A Novel Brain Stimulation Technology Provides Compatibility with MRI
title A Novel Brain Stimulation Technology Provides Compatibility with MRI
title_full A Novel Brain Stimulation Technology Provides Compatibility with MRI
title_fullStr A Novel Brain Stimulation Technology Provides Compatibility with MRI
title_full_unstemmed A Novel Brain Stimulation Technology Provides Compatibility with MRI
title_short A Novel Brain Stimulation Technology Provides Compatibility with MRI
title_sort novel brain stimulation technology provides compatibility with mri
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413880/
https://www.ncbi.nlm.nih.gov/pubmed/25924189
http://dx.doi.org/10.1038/srep09805
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