SIRT7 inactivation reverses metastatic phenotypes in epithelial and mesenchymal tumors

Metastasis is responsible for over 90% of cancer-associated mortality. In epithelial carcinomas, a key process in metastatic progression is the epigenetic reprogramming of an epithelial-to-mesenchymal transition-like (EMT) change towards invasive cellular phenotypes. In non-epithelial cancers, diffe...

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Detalles Bibliográficos
Autores principales: Malik, Shivani, Villanova, Lidia, Tanaka, Shinji, Aonuma, Misato, Roy, Nilotpal, Berber, Elisabeth, Pollack, Jonathan R., Michishita-Kioi, Eriko, Chua, Katrin F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4413894/
https://www.ncbi.nlm.nih.gov/pubmed/25923013
http://dx.doi.org/10.1038/srep09841

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