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From sequence to structure and back again: approaches for predicting protein-DNA binding

Gene regulation in higher organisms is achieved by a complex network of transcription factors (TFs). Modulating gene expression and exploring gene function are major aims in molecular biology. Furthermore, the identification of putative target genes for a certain TF serve as powerful tools for speci...

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Detalles Bibliográficos
Autores principales: Höglund, Annette, Kohlbacher, Oliver
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2004
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC441406/
https://www.ncbi.nlm.nih.gov/pubmed/15202939
http://dx.doi.org/10.1186/1477-5956-2-3

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