Roles of c-Met and RON kinases in tumor progression and their potential as therapeutic targets

c-Met and receptor originated from nantes (RON) are structurally related transmembrane phosphotyrosine kinase receptors. c-Met and RON show increased expression or activity in a variety of tumors leading to tumor progression and may play a role in acquired resistance to therapy. Although often co-ex...

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Detalles Bibliográficos
Autores principales: Chang, Katherine, Karnad, Anand, Zhao, Shujie, Freeman, James W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414132/
https://www.ncbi.nlm.nih.gov/pubmed/25784650

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