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Cyclosporin A differentially inhibits multiple steps in VEGF induced angiogenesis in human microvascular endothelial cells through altered intracellular signaling
The immunosuppressive agent cyclosporin A (CsA), a calcineurin inhibitor which blocks T cell activation has provided the pharmacologic foundation for organ transplantation. CsA exerts additional effects on non-immune cell populations and may adversely effect microvascular endothelial cells, contribu...
Autores principales: | Rafiee, Parvaneh, Heidemann, Jan, Ogawa, Hitoshi, Johnson, Nathan A, Fisher, Pamela J, Li, Mona S, Otterson, Mary F, Johnson, Christopher P, Binion, David G |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2004
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC441414/ https://www.ncbi.nlm.nih.gov/pubmed/15175101 http://dx.doi.org/10.1186/1478-811X-2-3 |
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