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The function of cux1 in oxidative dna damage repair is needed to prevent premature senescence of mouse embryo fibroblasts

Despite having long telomeres, mouse embryo fibroblasts (MEFs) senesce more rapidly than human diploid fibroblasts because of the accumulation of oxidative DNA damage. The CUX1 homeodomain protein was recently found to prevent senescence in RAS-driven cancer cells that produce elevated levels of rea...

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Detalles Bibliográficos
Autores principales:	Ramdzan, Zubaidah M., Pal, Ranjana, Kaur, Simran, Leduy, Lam, Bérubé, Ginette, Davoudi, Sayeh, Vadnais, Charles, Nepveu, Alain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2015
Materias:	Gerotarget (Focus on Aging): Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414141/ https://www.ncbi.nlm.nih.gov/pubmed/25682875

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