Oncoprotein mdig contributes to silica-induced pulmonary fibrosis by altering balance between Th17 and Treg T cells

Mineral dust-induced gene (mdig, also named Mina53) was first identified from alveolar macrophages of the coal miners with chronic lung inflammation or fibrosis, but how this gene is involved in lung diseases is poorly understood. Here we show that heterozygotic knockout of mdig (mdig+/−) ameliorate...

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Detalles Bibliográficos
Autores principales: Thakur, Chitra, Wolfarth, Michael, Sun, Jiaying, Zhang, Yadong, Lu, Yongju, Battelli, Lori, Porter, Dale W., Chen, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414149/
https://www.ncbi.nlm.nih.gov/pubmed/25669985

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