Protease nexin 1 induces apoptosis of prostate tumor cells through inhibition of X-chromosome-linked inhibitor of apoptosis protein

Protease nexin 1 (PN1) is an endogenous serine protease inhibitor (SERPIN), expressed at high levels in the prostate, and capable of inhibiting the proliferation of prostate cancer cells. We previously showed that PN1-uPA complexes inhibited Sonic Hedgehog (SHH) signalling through engagement of the...

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Detalles Bibliográficos
Autores principales: McKee, Chad M., Ding, Yunchuan, Zhou, Jianfeng, Li, Chunrui, Huang, Liang, Xin, Xiangke, He, Jing, Allen, Joshua E., El-Deiry, Wafik S., Cao, Yunhong, Muschel, Ruth J., Xu, Danmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414153/
https://www.ncbi.nlm.nih.gov/pubmed/25686839

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