NF-κB signaling mediates acquired resistance after PARP inhibition

PARP inhibitors are a class of promising anti-cancer drugs, with proven activity in BRCA mutant cancers. However, as with other targeted agents, treatment with PARP inhibitors generates acquired resistance within these tumors. The mechanism of this acquired resistance is poorly understood. We establ...

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Detalles Bibliográficos
Autores principales: Nakagawa, Yuko, Sedukhina, Anna S., Okamoto, Naoki, Nagasawa, Satoi, Suzuki, Nao, Ohta, Tomohiko, Hattori, Hiroyoshi, Roche-Molina, Marta, Narváez, Ana J., Jeyasekharan, Anand D., Bernal, Juan A., Sato, Ko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414156/
https://www.ncbi.nlm.nih.gov/pubmed/25686825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414156/
https://www.ncbi.nlm.nih.gov/pubmed/25686825

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