Morphine promotes cancer stem cell properties, contributing to chemoresistance in breast cancer

Morphine is an opioid analgesic drug commonly used for pain relief in cancer patients. Here, we report that morphine enhances the mammosphere forming capacity and increases the expression of stemness-related transcription factors Oct4, Sox2 and Nanog. Treatment with morphine leads to enrichment of a...

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Detalles Bibliográficos
Autores principales: Niu, Dong-Ge, Peng, Fei, Zhang, Wei, Guan, Zhong, Zhao, Hai-Dong, Li, Jing-Lin, Wang, Kai-Li, Li, Ting-Ting, Zhang, Yan, Zheng, Fei-Meng, Xu, Fan, Han, Qian-Ni, Gao, Peng, Wen, Qing-Ping, Liu, Quentin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414166/
https://www.ncbi.nlm.nih.gov/pubmed/25686831

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