miR-34a induces cellular senescence via modulation of telomerase activity in human hepatocellular carcinoma by targeting FoxM1/c-Myc pathway

Increasing evidence suggests that miRNAs can act as either tumor suppressors or oncogenes in carcinogenesis. In the present study, we identified the role of miR-34a in regulating telomerase activity, with subsequent effect on cellular senescence and viability. We found the higher expression of miR-3...

Descripción completa

Detalles Bibliográficos
Autores principales: Xu, Xinsen, Chen, Wei, Miao, Runchen, Zhou, Yanyan, Wang, Zhixin, Zhang, Lingqiang, Wan, Yong, Dong, Yafeng, Qu, Kai, Liu, Chang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414168/
https://www.ncbi.nlm.nih.gov/pubmed/25686834

Ejemplares similares

Ejemplares similares