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Farnesoid X receptor associates with β-catenin and inhibits its activity in hepatocellular carcinoma

The association between the temporal activation of Wnt/β-catenin pathway and the spontaneous hepatocellular carcinoma (HCC) development in Farnesoid X receptor (FXR) knockout mice is not well understood. We found that Huh7 cells depleted with FXR by RNAi showed enhanced cell growth, migration and in...

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Detalles Bibliográficos
Autores principales: Liu, Xijun, Zhang, Xingwang, Ji, Lingling, Gu, Jianxin, Zhou, Meiling, Chen, She
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414185/
https://www.ncbi.nlm.nih.gov/pubmed/25650661