Cargando…
GATA1 induces epithelial-mesenchymal transition in breast cancer cells through PAK5 oncogenic signaling
Epithelial-mesenchymal transition (EMT) is a key process in tumor metastatic cascade that is characterized by the loss of cell-cell junctions, resulting in the acquisition of migratory and invasive properties. E-cadherin is a major component of intercellular junctions and the reduction or loss of it...
Autores principales: | Li, Yang, Ke, Qiang, Shao, Yangguang, Zhu, Ge, Li, Yanshu, Geng, Nanxi, Jin, Feng, Li, Feng |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414194/ https://www.ncbi.nlm.nih.gov/pubmed/25726523 |
Ejemplares similares
-
A mandatory role of nuclear PAK4-LIFR axis in breast-to-bone metastasis of ERα-positive breast cancer cells
por: Li, Yanshu, et al.
Publicado: (2018) -
GATA6 promotes epithelial-mesenchymal transition and metastasis through MUC1/β-catenin pathway in cholangiocarcinoma
por: Deng, Xiang, et al.
Publicado: (2020) -
PAK4 regulates G6PD activity by p53 degradation involving colon cancer cell growth
por: Zhang, Xiumei, et al.
Publicado: (2017) -
PAK5-mediated AIF phosphorylation inhibits its nuclear translocation and promotes breast cancer tumorigenesis
por: Xing, Yao, et al.
Publicado: (2021) -
Group I Paks are essential for epithelial- mesenchymal transition in an Apc-driven model of colorectal cancer
por: Chow, H. Y., et al.
Publicado: (2018)