Cargando…

Mesenchymal stem cells-regulated Treg cells suppress colitis-associated colorectal cancer

INTRODUCTION: Previous studies have produced controversial results regarding whether mesenchymal stem cells (MSCs) promote or inhibit tumor development. Given the dual role of MSCs in inflammation and cancer, in this study the colitis-associated colorectal cancer (CAC) model was used to examine whet...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tang, Rui-jing, Shen, Su-nan, Zhao, Xiao-yin, Nie, Yun-zhong, Xu, Yu-jun, Ren, Jing, Lv, Ming-ming, Hou, Ya-yi, Wang, Ting-ting
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414289/ https://www.ncbi.nlm.nih.gov/pubmed/25889203 http://dx.doi.org/10.1186/s13287-015-0055-8

Ejemplares similares

Cambogin suppresses dextran sulphate sodium‐induced colitis by enhancing Treg cell stability and function
por: Lu, Yue, et al.
Publicado: (2018)

Olfactory Ecto-Mesenchymal Stem Cell-Derived Exosomes Ameliorate Experimental Colitis via Modulating Th1/Th17 and Treg Cell Responses
por: Tian, Jie, et al.
Publicado: (2020)

Circadian Clock Disruption Suppresses PDL1(+) Intraepithelial B Cells in Experimental Colitis and Colitis-Associated Colorectal Cancer
por: Liu, Jing-Lin, et al.
Publicado: (2021)

Butyrate inhibits interleukin-17 and generates Tregs to ameliorate colorectal colitis in rats
por: Zhang, Mingming, et al.
Publicado: (2016)

RIP3 promotes colitis-associated colorectal cancer by controlling tumor cell proliferation and CXCL1-induced immune suppression
por: Liu, Zhen-Yu, et al.
Publicado: (2019)

Protective Role of Fecal Microbiota Transplantation on Colitis and Colitis-Associated Colon Cancer in Mice Is Associated With Treg Cells
por: Wang, Zitao, et al.
Publicado: (2019)

Cholesterol suppresses human iTreg differentiation and nTreg function through mitochondria-related mechanisms
por: Zhang, Huanzhi, et al.
Publicado: (2023)

Curcumin ameliorates DSS-induced colitis in mice by regulating the Treg/Th17 signaling pathway
por: Wei, Cheng, et al.
Publicado: (2021)

Circulating CD4(+) Treg, CD8(+) Treg, and CD3(+) γδ T Cell Subpopulations in Ovarian Cancer
por: Li, Rong, et al.
Publicado: (2023)

Molecular Mechanisms of Treg-Mediated T Cell Suppression
por: Schmidt, Angelika, et al.
Publicado: (2012)

Celastrol Ameliorates Ulcerative Colitis-Related Colorectal Cancer in Mice via Suppressing Inflammatory Responses and Epithelial-Mesenchymal Transition
por: Lin, Lianjie, et al.
Publicado: (2016)

Recombinant adeno-associated virus carrying thymosin β(4) suppresses experimental colitis in mice
por: Zheng, Xiao-Yan, et al.
Publicado: (2017)

Human Amniotic Mesenchymal Stem Cells Inhibit aGVHD by Regulating Balance of Treg and T Effector Cells
por: Gao, Ya, et al.
Publicado: (2021)

Mesenchymal Stem Cell Induced Foxp3(+) Tregs Suppress Effector T Cells and Protect against Retinal Ischemic Injury
por: Agrawal, Mona, et al.
Publicado: (2021)

Doxycycline reverses epithelial-to-mesenchymal transition and suppresses the proliferation and metastasis of lung cancer cells
por: Qin, Yuan, et al.
Publicado: (2015)

Stigmasterol Restores the Balance of Treg/Th17 Cells by Activating the Butyrate-PPARγ Axis in Colitis
por: Wen, Shuting, et al.
Publicado: (2021)

Calcitriol Suppresses Warburg Effect and Cell Growth in Human Colorectal Cancer Cells
por: Huang, Chun-Yin, et al.
Publicado: (2021)

Exosomal miR-208b related with oxaliplatin resistance promotes Treg expansion in colorectal cancer
por: Ning, Tao, et al.
Publicado: (2021)

mTOR Inhibition Attenuates Dextran Sulfate Sodium-Induced Colitis by Suppressing T Cell Proliferation and Balancing TH1/TH17/Treg Profile
por: Hu, Shurong, et al.
Publicado: (2016)

High‐dose wogonin exacerbates DSS‐induced colitis by up‐regulating effector T cell function and inhibiting Treg cell
por: Xiao, Weiming, et al.
Publicado: (2016)

Adoptive Transfer of Treg Cells Combined with Mesenchymal Stem Cells Facilitates Repopulation of Endogenous Treg Cells in a Murine Acute GVHD Model
por: Lee, Eun-Sol, et al.
Publicado: (2015)

Are aged pTreg cells “the more the better”?
por: Wang, Weikan, et al.
Publicado: (2022)

Proanthocyanidins: novel treatment for psoriasis that reduces oxidative stress and modulates Th17 and Treg cells
por: Lai, Rui, et al.
Publicado: (2018)

Plasmodium yoelii 17XL infection modified maturation and function of dendritic cells by skewing Tregs and amplificating Th17
por: Chen, Guang, et al.
Publicado: (2020)

Rapid expansion of Treg cells protects from collateral colitis following a viral trigger
por: Schorer, Michelle, et al.
Publicado: (2020)

Change in the Treg/Th17 cell imbalance in hepatocellular carcinoma patients and its clinical value
por: Lan, Yong-Ting, et al.
Publicado: (2017)

BMSCs improve TNBS-induced colitis in rats by inducing Treg differentiation by expressing PD-L1
por: Gao, Fei, et al.
Publicado: (2022)

Mesenchymal Stem Cell-Secreted TGF-β1 Restores Treg/Th17 Skewing Induced by Lipopolysaccharide and Hypoxia Challenge via miR-155 Suppression
por: Xue, Ming, et al.
Publicado: (2022)

In situ conversion of defective Treg into SuperTreg cells to treat advanced IPEX-like disorders in mice
por: Li, Yongqin, et al.
Publicado: (2020)

HSF1 promotes CD69(+) Treg differentiation to inhibit colitis progression
por: Yu, Lei, et al.
Publicado: (2023)

Adipose-derived mesenchymal stem cells may reduce intestinal epithelial damage in ulcerative colitis by communicating with macrophages and blocking inflammatory pathways: an analysis in silico
por: Zhang, Nan, et al.
Publicado: (2022)

miR-497 suppresses epithelial–mesenchymal transition and metastasis in colorectal cancer cells by targeting fos-related antigen-1
por: Zhang, Nan, et al.
Publicado: (2016)

Multiple treg suppressive modules and their adaptability
por: Wing, James B., et al.
Publicado: (2012)

Inflammasomes in Colitis and Colorectal Cancer: Mechanism of Action and Therapies
por: Pandey, Abhimanu, et al.
Publicado: (2019)

Effects of Huaier Extract on Ameliorating Colitis-Associated Colorectal Tumorigenesis in Mice
por: Zou, Yi-feng, et al.
Publicado: (2020)

The Different Functional Distribution of “Not Effector” T Cells (Treg/Tnull) in Colorectal Cancer
por: Niccolai, Elena, et al.
Publicado: (2017)

Labial gland-derived mesenchymal stem cells and their exosomes ameliorate murine Sjögren's syndrome by modulating the balance of Treg and Th17 cells
por: Li, Boya, et al.
Publicado: (2021)

Inhibition of Cdk8/Cdk19 Activity Promotes Treg Cell Differentiation and Suppresses Autoimmune Diseases
por: Guo, Zengli, et al.
Publicado: (2019)

Ulcerative Colitis in Response to Fecal Microbiota Transplantation via Modulation of Gut Microbiota and Th17/Treg Cell Balance
por: Huang, Chunlan, et al.
Publicado: (2022)

Qingchang Huashi granule ameliorates experimental colitis via restoring the dendritic cell-mediated Th17/Treg balance
por: Jia, Jia, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_r488agtvv5979nvqea57jbm5ca