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Timing of Complementary Food Introduction and Age at Diagnosis of Type 1 Diabetes: the SEARCH Nutrition Ancillary STUDY (SNAS)

The association between timing of complementary food introduction and age at diagnosis of type 1 diabetes was investigated among 1077 children in the SEARCH for Diabetes in Youth study. Age at diagnosis was 5-month earlier for children introduced to sugar-sweetened beverages (SSB) in the first 12 mo...

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Autores principales: Crume, Tessa L., Crandell, Jamie, Norris, Jill M., Dabelea, Dana, Fangman, Mary T., Pettitt, David J., Dolan, Lawrence, Rodriguez, Beatriz L., O'Connor, Rebecca, Mayer-Davis, Elizabeth J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414319/
https://www.ncbi.nlm.nih.gov/pubmed/25117987
http://dx.doi.org/10.1038/ejcn.2014.159
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author Crume, Tessa L.
Crandell, Jamie
Norris, Jill M.
Dabelea, Dana
Fangman, Mary T.
Pettitt, David J.
Dolan, Lawrence
Rodriguez, Beatriz L.
O'Connor, Rebecca
Mayer-Davis, Elizabeth J.
author_facet Crume, Tessa L.
Crandell, Jamie
Norris, Jill M.
Dabelea, Dana
Fangman, Mary T.
Pettitt, David J.
Dolan, Lawrence
Rodriguez, Beatriz L.
O'Connor, Rebecca
Mayer-Davis, Elizabeth J.
author_sort Crume, Tessa L.
collection PubMed
description The association between timing of complementary food introduction and age at diagnosis of type 1 diabetes was investigated among 1077 children in the SEARCH for Diabetes in Youth study. Age at diagnosis was 5-month earlier for children introduced to sugar-sweetened beverages (SSB) in the first 12 months of life compared to those who were not (9.0 ± 0.2 vs. 9.5 ± 0.1; p=0.02), independent of HLA-risk status. Analyses stratified by HLA-risk status found that children with a high risk HLA genotype had an earlier age at diagnosis if they were introduced to fruit juice in the first year of life (mean age of diagnosis=9.3 ± 0.1, 9.1 ± 0.1 and 9.6 ± 0.2 for introduction at ≤ 6 months, between 7 and 11 months, and ≤12 months, respectively; p=0.04). Introduction of SSB in the first year of life may accelerate onset of type 1 diabetes independent of HLA-risk status.
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spelling pubmed-44143192015-05-01 Timing of Complementary Food Introduction and Age at Diagnosis of Type 1 Diabetes: the SEARCH Nutrition Ancillary STUDY (SNAS) Crume, Tessa L. Crandell, Jamie Norris, Jill M. Dabelea, Dana Fangman, Mary T. Pettitt, David J. Dolan, Lawrence Rodriguez, Beatriz L. O'Connor, Rebecca Mayer-Davis, Elizabeth J. Eur J Clin Nutr Article The association between timing of complementary food introduction and age at diagnosis of type 1 diabetes was investigated among 1077 children in the SEARCH for Diabetes in Youth study. Age at diagnosis was 5-month earlier for children introduced to sugar-sweetened beverages (SSB) in the first 12 months of life compared to those who were not (9.0 ± 0.2 vs. 9.5 ± 0.1; p=0.02), independent of HLA-risk status. Analyses stratified by HLA-risk status found that children with a high risk HLA genotype had an earlier age at diagnosis if they were introduced to fruit juice in the first year of life (mean age of diagnosis=9.3 ± 0.1, 9.1 ± 0.1 and 9.6 ± 0.2 for introduction at ≤ 6 months, between 7 and 11 months, and ≤12 months, respectively; p=0.04). Introduction of SSB in the first year of life may accelerate onset of type 1 diabetes independent of HLA-risk status. 2014-08-13 2014-11 /pmc/articles/PMC4414319/ /pubmed/25117987 http://dx.doi.org/10.1038/ejcn.2014.159 Text en http://www.nature.com/authors/editorial_policies/license.html#terms Users may view, print, copy, and download text and data-mine the content in such documents, for the purposes of academic research, subject always to the full Conditions of use:http://www.nature.com/authors/editorial_policies/license.html#terms
spellingShingle Article
Crume, Tessa L.
Crandell, Jamie
Norris, Jill M.
Dabelea, Dana
Fangman, Mary T.
Pettitt, David J.
Dolan, Lawrence
Rodriguez, Beatriz L.
O'Connor, Rebecca
Mayer-Davis, Elizabeth J.
Timing of Complementary Food Introduction and Age at Diagnosis of Type 1 Diabetes: the SEARCH Nutrition Ancillary STUDY (SNAS)
title Timing of Complementary Food Introduction and Age at Diagnosis of Type 1 Diabetes: the SEARCH Nutrition Ancillary STUDY (SNAS)
title_full Timing of Complementary Food Introduction and Age at Diagnosis of Type 1 Diabetes: the SEARCH Nutrition Ancillary STUDY (SNAS)
title_fullStr Timing of Complementary Food Introduction and Age at Diagnosis of Type 1 Diabetes: the SEARCH Nutrition Ancillary STUDY (SNAS)
title_full_unstemmed Timing of Complementary Food Introduction and Age at Diagnosis of Type 1 Diabetes: the SEARCH Nutrition Ancillary STUDY (SNAS)
title_short Timing of Complementary Food Introduction and Age at Diagnosis of Type 1 Diabetes: the SEARCH Nutrition Ancillary STUDY (SNAS)
title_sort timing of complementary food introduction and age at diagnosis of type 1 diabetes: the search nutrition ancillary study (snas)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414319/
https://www.ncbi.nlm.nih.gov/pubmed/25117987
http://dx.doi.org/10.1038/ejcn.2014.159
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