Impact of Toceranib/Piroxicam/Cyclophosphamide Maintenance Therapy on Outcome of Dogs with Appendicular Osteosarcoma following Amputation and Carboplatin Chemotherapy: A Multi-Institutional Study

BACKGROUND: We hypothesized that the addition of toceranib to metronomic cyclophosphamide/piroxicam therapy would significantly improve disease-free interval (DFI) and overall survival (OS) in dogs with appendicular osteosarcoma (OSA) following amputation and carboplatin chemotherapy. METHODS AND FI...

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Detalles Bibliográficos
Autores principales: London, Cheryl A., Gardner, Heather L., Mathie, Tamra, Stingle, Nicole, Portela, Roberta, Pennell, Michael L., Clifford, Craig A., Rosenberg, Mona P., Vail, David M., Williams, Laurel E., Cronin, Kim L., Wilson-Robles, Heather, Borgatti, Antonella, Henry, Carolyn J., Bailey, Dennis B., Locke, Jennifer, Northrup, Nicole C., Crawford-Jakubiak, Martin, Gill, Virginia L., Klein, Mary K., Ruslander, David M., Thamm, Doug H., Phillips, Brenda, Post, Gerald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414350/
https://www.ncbi.nlm.nih.gov/pubmed/25923466
http://dx.doi.org/10.1371/journal.pone.0124889

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