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Andrographolide reduces cognitive impairment in young and mature AβPPswe/PS-1 mice
Alzheimer’s disease (AD) is a neurodegenerative disorder in which the amyloid-β (Aβ) oligomers are a key factor in synaptic impairment and in spatial memory decline associated with neuronal dysfunction. This impairment includes synaptic failure associated with the loss of synaptic proteins that cont...
Autores principales: | Serrano, Felipe G, Tapia-Rojas, Cheril, Carvajal, Francisco J, Hancke, Juan, Cerpa, Waldo, Inestrosa, Nibaldo C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414355/ https://www.ncbi.nlm.nih.gov/pubmed/25524173 http://dx.doi.org/10.1186/1750-1326-9-61 |
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