Cargando…

The Clostridium difficile Protease Cwp84 Modulates both Biofilm Formation and Cell-Surface Properties

Clostridium difficile is responsible for 15-20% of antibiotic-associated diarrheas, and nearly all cases of pseudomembranous colitis. Among the cell wall proteins involved in the colonization process, Cwp84 is a protease that cleaves the S-layer protein SlpA into two subunits. A cwp84 mutant was pre...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pantaléon, Véronique, Soavelomandroso, Anna Philibertine, Bouttier, Sylvie, Briandet, Romain, Roxas, Bryan, Chu, Michele, Collignon, Anne, Janoir, Claire, Vedantam, Gayatri, Candela, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414356/ https://www.ncbi.nlm.nih.gov/pubmed/25922949 http://dx.doi.org/10.1371/journal.pone.0124971

Ejemplares similares

Biofilm Structures in a Mono-Associated Mouse Model of Clostridium difficile Infection
por: Soavelomandroso, Anna P., et al.
Publicado: (2017)

Cwp84, a Clostridium difficile cysteine protease, exhibits conformational flexibility in the absence of its propeptide
por: Bradshaw, William J., et al.
Publicado: (2015)

The structure of the cysteine protease and lectin-like domains of Cwp84, a surface layer-associated protein from Clostridium difficile
por: Bradshaw, William J., et al.
Publicado: (2014)

Clostridium difficile in Ground Meat, France
por: Bouttier, Sylvie, et al.
Publicado: (2010)

Targeting Clostridium difficile Surface Components to Develop Immunotherapeutic Strategies Against Clostridium difficile Infection
por: Péchiné, Séverine, et al.
Publicado: (2018)

Toxin release mediated by the novel autolysin Cwp19 in Clostridium difficile
por: El Meouche, Imane, et al.
Publicado: (2018)

The molecular structure of the glycoside hydrolase domain of Cwp19 from Clostridium difficile
por: Bradshaw, William J., et al.
Publicado: (2017)

Clostridium difficile flagellin FliC: Evaluation as adjuvant and use in a mucosal vaccine against Clostridium difficile
por: Bruxelle, Jean-François, et al.
Publicado: (2017)

Clostridium difficile Cell Wall Protein CwpV Undergoes Enzyme-independent Intramolecular Autoproteolysis
por: Dembek, Marcin, et al.
Publicado: (2012)

Cwp2 from Clostridium difficile exhibits an extended three domain fold and cell adhesion in vitro
por: Bradshaw, William J., et al.
Publicado: (2017)

An Engineered Synthetic Biologic Protects Against Clostridium difficile Infection
por: Vedantam, Gayatri, et al.
Publicado: (2018)

Surface-Layer Protein A (SlpA) Is a Major Contributor to Host-Cell Adherence of Clostridium difficile
por: Merrigan, Michelle M., et al.
Publicado: (2013)

Expression, purification, crystallization and preliminary crystallographic analysis of a putative Clostridium difficile surface protein Cwp19
por: Kirby, Jonathan M., et al.
Publicado: (2011)

A Clostridium difficile Cell Wall Glycopolymer Locus Influences Bacterial Shape, Polysaccharide Production and Virulence
por: Chu, Michele, et al.
Publicado: (2016)

Inhibition of In Vitro Clostridioides difficile Biofilm Formation by the Probiotic Yeast Saccharomyces boulardii CNCM I-745 through Modification of the Extracellular Matrix Composition
por: Lacotte, Pierre-Alexandre, et al.
Publicado: (2022)

Cwp19 Is a Novel Lytic Transglycosylase Involved in Stationary-Phase Autolysis Resulting in Toxin Release in Clostridium difficile
por: Wydau-Dematteis, Sandra, et al.
Publicado: (2018)

Peptidoglycan analysis reveals that synergistic deacetylase activity in vegetative Clostridium difficile impacts the host response
por: Coullon, Héloise, et al.
Publicado: (2021)

Deciphering Adaptation Strategies of the Epidemic Clostridium difficile 027 Strain during Infection through In Vivo Transcriptional Analysis
por: Kansau, Imad, et al.
Publicado: (2016)

The Clostridium difficile Cell Wall Protein CwpV is Antigenically Variable between Strains, but Exhibits Conserved Aggregation-Promoting Function
por: Reynolds, Catherine B., et al.
Publicado: (2011)

A novel genetic switch controls phase variable expression of CwpV, a Clostridium difficile cell wall protein
por: Emerson, Jenny E, et al.
Publicado: (2009)

A microbiota-generated bile salt induces biofilm formation in Clostridium difficile
por: Dubois, Thomas, et al.
Publicado: (2019)

Expanding the Repertoire of Gene Tools for Precise Manipulation of the Clostridium difficile Genome: Allelic Exchange Using pyrE Alleles
por: Ng, Yen Kuan, et al.
Publicado: (2013)

Clostridium difficile flagella induce a pro-inflammatory response in intestinal epithelium of mice in cooperation with toxins
por: Batah, Jameel, et al.
Publicado: (2017)

Toxin B is essential for virulence of Clostridium difficile
por: Lyras, Dena, et al.
Publicado: (2009)

The cwp66 Gene Affects Cell Adhesion, Stress Tolerance, and Antibiotic Resistance in Clostridioides difficile
por: Zhou, Qingshuai, et al.
Publicado: (2022)

Low-toxin Clostridioides difficile RT027 strains exhibit robust virulence
por: Anwar, Farhan, et al.
Publicado: (2022)

Nonsteroidal Anti-inflammatory Drugs Alter the Microbiota and Exacerbate Clostridium difficile Colitis while Dysregulating the Inflammatory Response
por: Maseda, Damian, et al.
Publicado: (2019)

The C lostridium difficile cell wall protein CwpV confers phase‐variable phage resistance
por: Sekulovic, Ognjen, et al.
Publicado: (2015)

Clostridium difficile Biofilm: Remodeling Metabolism and Cell Surface to Build a Sparse and Heterogeneously Aggregated Architecture
por: Poquet, Isabelle, et al.
Publicado: (2018)

The Alternative Sigma Factor SigL Influences Clostridioides difficile Toxin Production, Sporulation, and Cell Surface Properties
por: Clark, Andrew E., et al.
Publicado: (2022)

Virulence of new variant strains of Clostridium difficile producing only toxin A or binary toxin in the hamster model
por: Marvaud, J.-C., et al.
Publicado: (2019)

Anti-virulence strategies for Clostridioides difficile infection: advances and roadblocks
por: Stewart, David, et al.
Publicado: (2020)

Immunization Using GroEL Decreases Clostridium difficile Intestinal Colonization
por: Péchiné, Séverine, et al.
Publicado: (2013)

Low temperature upregulates cwp expression and modifies alternative splicing patterns, increasing the severity of cwp-induced tomato fruit cuticular microfissures
por: Chechanovsky, Noam, et al.
Publicado: (2019)

Identification of Novel Pathogenicity Loci in Clostridium perfringens Strains That Cause Avian Necrotic Enteritis
por: Lepp, Dion, et al.
Publicado: (2010)

Extracellular succinate induces spatially organized biofilm formation in Clostridioides difficile
por: Auria, Emile, et al.
Publicado: (2023)

Defining an allosteric circuit in the cysteine protease domain of Clostridium difficile toxins
por: Shen, Aimee, et al.
Publicado: (2011)

Correction: Identification of Novel Pathogenicity Loci in Clostridium perfringens Strains That Cause Avian Necrotic Enteritis
por: Lepp, Dion, et al.
Publicado: (2010)

Phylogenomic analysis of Clostridioides difficile ribotype 106 strains reveals novel genetic islands and emergent phenotypes
por: Roxas, Bryan Angelo P., et al.
Publicado: (2020)

The Flagellin FliC of Clostridium difficile Is Responsible for Pleiotropic Gene Regulation during In Vivo Infection
por: Barketi-Klai, Amira, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ju1kf3fnu8kep923fhomjq0m35