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The development of drug resistance mutations K103N Y181C and G190A in long term Nevirapine-containing antiviral therapy

OBJECTIVE: We built a cohort study of HIV patients taking long-term first-line Antiretroviral Therapy in 2003. In this assay, we focused on the development of primary drug resistance mutations against Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI), K103N, Y181C and G190A. METHOD: The cohort...

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Detalles Bibliográficos
Autores principales: Wang, Yuncong, Xing, Hui, Liao, Lingjie, Wang, Zhe, Su, Bin, Zhao, Quanbi, Feng, Yi, Ma, Pengfei, Liu, Jia, Wu, Jianjun, Ruan, Yuhua, Shao, Yiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414387/
https://www.ncbi.nlm.nih.gov/pubmed/25926857
http://dx.doi.org/10.1186/1742-6405-11-36