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Three-Dimensional Gradients of Cytokine Signaling between T Cells
Immune responses are regulated by diffusible mediators, the cytokines, which act at sub-nanomolar concentrations. The spatial range of cytokine communication is a crucial, yet poorly understood, functional property. Both containment of cytokine action in narrow junctions between immune cells (immuno...
Autores principales: | Thurley, Kevin, Gerecht, Daniel, Friedmann, Elfriede, Höfer, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414419/ https://www.ncbi.nlm.nih.gov/pubmed/25923703 http://dx.doi.org/10.1371/journal.pcbi.1004206 |
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