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Human hepatic stem cells transplanted into a fulminant hepatic failure Alb-TRECK/SCID mouse model exhibit liver reconstitution and drug metabolism capabilities

INTRODUCTION: Chimeric mice with humanized livers were recently established by transplanting human hepatocytes. This mouse model that is repopulated with functional human hepatocytes could be a useful tool for investigating human hepatic cell biology and drug metabolism and for other preclinical app...

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Detalles Bibliográficos
Autores principales:	Zhang, Ran-Ran, Zheng, Yun-Wen, Li, Bin, Tsuchida, Tomonori, Ueno, Yasuharu, Nie, Yun-Zhong, Taniguchi, Hideki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414454/ https://www.ncbi.nlm.nih.gov/pubmed/25889844 http://dx.doi.org/10.1186/s13287-015-0038-9

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