Susceptibility to tuberculosis is associated with variants in the ASAP1 gene encoding a regulator of dendritic cell migration

Human genetic factors predispose to tuberculosis (TB). We studied 7.6 million genetic variants in 5,530 pulmonary TB patients and 5,607 healthy controls. In the combined analysis of these subjects and the follow-up cohort (15,087 TB patients and controls altogether), we found association between TB...

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Detalles Bibliográficos
Autores principales: Curtis, James, Luo, Yang, Zenner, Helen L., Cuchet-Lourenço, Delphine, Wu, Changxin, Lo, Kitty, Maes, Mailis, Alisaac, Ali, Stebbings, Emma, Liu, Jimmy Z., Kopanitsa, Liliya, Ignatyeva, Olga, Balabanova, Yanina, Nikolayevskyy, Vladyslav, Baessmann, Ingelore, Thye, Thorsten, Meyer, Christian G., Nürnberg, Peter, Horstmann, Rolf D., Drobniewski, Francis, Plagnol, Vincent, Barrett, Jeffrey C., Nejentsev, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414475/
https://www.ncbi.nlm.nih.gov/pubmed/25774636
http://dx.doi.org/10.1038/ng.3248

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