Dexamethasone Treatment of Newborn Rats Decreases Cardiomyocyte Endowment in the Developing Heart through Epigenetic Modifications

The potential adverse effect of synthetic glucocorticoid, dexamethasone therapy on the developing heart remains unknown. The present study investigated the effects of dexamethasone on cardiomyocyte proliferation and binucleation in the developing heart of newborn rats and evaluated DNA methylation a...

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Detalles Bibliográficos
Autores principales: Gay, Maresha S., Li, Yong, Xiong, Fuxia, Lin, Thant, Zhang, Lubo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414482/
https://www.ncbi.nlm.nih.gov/pubmed/25923220
http://dx.doi.org/10.1371/journal.pone.0125033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414482/
https://www.ncbi.nlm.nih.gov/pubmed/25923220
http://dx.doi.org/10.1371/journal.pone.0125033

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