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Cluster of Serogroup W-135 Meningococcal Disease in 3 Military Recruits

We describe a group of 3 cases of invasive meningococcal disease that occurred in a military training camp in April 2011. All three patients were hospitalized. Ultimately, two patients recovered and one died. One patient had meningitis, one patient had septicemia and meningitis, and the other had no...

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Autores principales: Jo, Yu Mi, Bae, Song-Mee, Kang, Yeon-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414654/
https://www.ncbi.nlm.nih.gov/pubmed/25931801
http://dx.doi.org/10.3346/jkms.2015.30.5.662
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author Jo, Yu Mi
Bae, Song-Mee
Kang, Yeon-Ho
author_facet Jo, Yu Mi
Bae, Song-Mee
Kang, Yeon-Ho
author_sort Jo, Yu Mi
collection PubMed
description We describe a group of 3 cases of invasive meningococcal disease that occurred in a military training camp in April 2011. All three patients were hospitalized. Ultimately, two patients recovered and one died. One patient had meningitis, one patient had septicemia and meningitis, and the other had no definite septicemia or meningitis. Neisseria meningitidis serogroup W-135 was detected in the serum and cerebrospinal fluid (CSF) of all patients by real-time polymerase chain reaction. In the one case of mortality, two strains were isolated from the patient's blood and CSF. Using multilocus sequence typing analysis, these strains were identified as a novel sequence type, ST-8912. Special attention is required for the meningococcal disease in military camp because the military personnels are in high risk of contact transmission. GRAPHICAL ABSTRACT: [Image: see text]
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spelling pubmed-44146542015-05-01 Cluster of Serogroup W-135 Meningococcal Disease in 3 Military Recruits Jo, Yu Mi Bae, Song-Mee Kang, Yeon-Ho J Korean Med Sci Case Report We describe a group of 3 cases of invasive meningococcal disease that occurred in a military training camp in April 2011. All three patients were hospitalized. Ultimately, two patients recovered and one died. One patient had meningitis, one patient had septicemia and meningitis, and the other had no definite septicemia or meningitis. Neisseria meningitidis serogroup W-135 was detected in the serum and cerebrospinal fluid (CSF) of all patients by real-time polymerase chain reaction. In the one case of mortality, two strains were isolated from the patient's blood and CSF. Using multilocus sequence typing analysis, these strains were identified as a novel sequence type, ST-8912. Special attention is required for the meningococcal disease in military camp because the military personnels are in high risk of contact transmission. GRAPHICAL ABSTRACT: [Image: see text] The Korean Academy of Medical Sciences 2015-05 2015-04-15 /pmc/articles/PMC4414654/ /pubmed/25931801 http://dx.doi.org/10.3346/jkms.2015.30.5.662 Text en © 2015 The Korean Academy of Medical Sciences. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Jo, Yu Mi
Bae, Song-Mee
Kang, Yeon-Ho
Cluster of Serogroup W-135 Meningococcal Disease in 3 Military Recruits
title Cluster of Serogroup W-135 Meningococcal Disease in 3 Military Recruits
title_full Cluster of Serogroup W-135 Meningococcal Disease in 3 Military Recruits
title_fullStr Cluster of Serogroup W-135 Meningococcal Disease in 3 Military Recruits
title_full_unstemmed Cluster of Serogroup W-135 Meningococcal Disease in 3 Military Recruits
title_short Cluster of Serogroup W-135 Meningococcal Disease in 3 Military Recruits
title_sort cluster of serogroup w-135 meningococcal disease in 3 military recruits
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414654/
https://www.ncbi.nlm.nih.gov/pubmed/25931801
http://dx.doi.org/10.3346/jkms.2015.30.5.662
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