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Capillary lactate as a tool for the triage nurse among patients with SIRS at emergency department presentation: a preliminary report

BACKGROUND: The triage nurse is involved in the early identification of the most severe patients at emergency department (ED) presentation. However, clinical criteria alone may be insufficient to identify them correctly. Measurement of capillary lactate concentration at ED presentation may help to d...

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Autores principales: Manzon, Cyril, Barrot, Loïc, Besch, Guillaume, Barbot, Olivier, Desmettre, Thibaut, Capellier, Gilles, Piton, Gaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Paris 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414858/
https://www.ncbi.nlm.nih.gov/pubmed/25977833
http://dx.doi.org/10.1186/s13613-015-0047-y
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author Manzon, Cyril
Barrot, Loïc
Besch, Guillaume
Barbot, Olivier
Desmettre, Thibaut
Capellier, Gilles
Piton, Gaël
author_facet Manzon, Cyril
Barrot, Loïc
Besch, Guillaume
Barbot, Olivier
Desmettre, Thibaut
Capellier, Gilles
Piton, Gaël
author_sort Manzon, Cyril
collection PubMed
description BACKGROUND: The triage nurse is involved in the early identification of the most severe patients at emergency department (ED) presentation. However, clinical criteria alone may be insufficient to identify them correctly. Measurement of capillary lactate concentration at ED presentation may help to discriminate these patients. The primary objective of this study was to identify the prognostic value of capillary lactate concentration measured by the triage nurse among patients presenting to the ED. METHODS: This was a prospective observational study, performed in the ED of a university hospital. At ED presentation, capillary lactate measurement was performed by the triage nurse among patients presenting with a clinical criteria of systemic inflammatory response syndrome (SIRS). Clinical variables usually used to determine severity were collected at presentation. Twenty-eight-day mortality and MEDS score were recorded. RESULTS: One hundred seventy-six patients with clinical SIRS presented to the ED. Median age was 72 years, and 28-day mortality was 16%. Capillary lactate at ED presentation was significantly higher among 28-day non-survivors than among survivors (5.7 mmol.L(−1) [3.2 to 7.4] vs 2.9 mmol.L(−1) [1.9 to 5.2], p = 0.003). A score based on mottling and capillary lactate concentration >3.6 mmol.L(−1) was significantly associated with 28-day mortality (area under curve, AUC = 0.75), independently of the MEDS score (AUC = 0.79) for the prediction of 28-day mortality (AUC global model 0.87). CONCLUSIONS: A high capillary lactate concentration measured by the triage nurse among patients presenting to the ED with clinical SIRS is associated with a high risk of death. A score calculated by the triage nurse, based on mottling and capillary lactate concentration, appears to be useful for identifying the most severe patients.
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spelling pubmed-44148582015-05-14 Capillary lactate as a tool for the triage nurse among patients with SIRS at emergency department presentation: a preliminary report Manzon, Cyril Barrot, Loïc Besch, Guillaume Barbot, Olivier Desmettre, Thibaut Capellier, Gilles Piton, Gaël Ann Intensive Care Research BACKGROUND: The triage nurse is involved in the early identification of the most severe patients at emergency department (ED) presentation. However, clinical criteria alone may be insufficient to identify them correctly. Measurement of capillary lactate concentration at ED presentation may help to discriminate these patients. The primary objective of this study was to identify the prognostic value of capillary lactate concentration measured by the triage nurse among patients presenting to the ED. METHODS: This was a prospective observational study, performed in the ED of a university hospital. At ED presentation, capillary lactate measurement was performed by the triage nurse among patients presenting with a clinical criteria of systemic inflammatory response syndrome (SIRS). Clinical variables usually used to determine severity were collected at presentation. Twenty-eight-day mortality and MEDS score were recorded. RESULTS: One hundred seventy-six patients with clinical SIRS presented to the ED. Median age was 72 years, and 28-day mortality was 16%. Capillary lactate at ED presentation was significantly higher among 28-day non-survivors than among survivors (5.7 mmol.L(−1) [3.2 to 7.4] vs 2.9 mmol.L(−1) [1.9 to 5.2], p = 0.003). A score based on mottling and capillary lactate concentration >3.6 mmol.L(−1) was significantly associated with 28-day mortality (area under curve, AUC = 0.75), independently of the MEDS score (AUC = 0.79) for the prediction of 28-day mortality (AUC global model 0.87). CONCLUSIONS: A high capillary lactate concentration measured by the triage nurse among patients presenting to the ED with clinical SIRS is associated with a high risk of death. A score calculated by the triage nurse, based on mottling and capillary lactate concentration, appears to be useful for identifying the most severe patients. Springer Paris 2015-04-24 /pmc/articles/PMC4414858/ /pubmed/25977833 http://dx.doi.org/10.1186/s13613-015-0047-y Text en © Manzon et al.; licensee Springer. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited.
spellingShingle Research
Manzon, Cyril
Barrot, Loïc
Besch, Guillaume
Barbot, Olivier
Desmettre, Thibaut
Capellier, Gilles
Piton, Gaël
Capillary lactate as a tool for the triage nurse among patients with SIRS at emergency department presentation: a preliminary report
title Capillary lactate as a tool for the triage nurse among patients with SIRS at emergency department presentation: a preliminary report
title_full Capillary lactate as a tool for the triage nurse among patients with SIRS at emergency department presentation: a preliminary report
title_fullStr Capillary lactate as a tool for the triage nurse among patients with SIRS at emergency department presentation: a preliminary report
title_full_unstemmed Capillary lactate as a tool for the triage nurse among patients with SIRS at emergency department presentation: a preliminary report
title_short Capillary lactate as a tool for the triage nurse among patients with SIRS at emergency department presentation: a preliminary report
title_sort capillary lactate as a tool for the triage nurse among patients with sirs at emergency department presentation: a preliminary report
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414858/
https://www.ncbi.nlm.nih.gov/pubmed/25977833
http://dx.doi.org/10.1186/s13613-015-0047-y
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