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Regulation of chromatin accessibility and Zic binding at enhancers in the developing cerebellum
To identify chromatin mechanisms of neuronal differentiation, we characterized chromatin accessibility and gene expression in cerebellar granule neurons (CGNs) of the developing mouse. We used DNase-seq to map accessibility of cis-regulatory elements and RNA-seq to profile transcript abundance acros...
Autores principales: | Frank, Christopher L., Liu, Fang, Wijayatunge, Ranjula, Song, Lingyun, Biegler, Matthew T., Yang, Marty G., Vockley, Christopher M., Safi, Alexias, Gersbach, Charles A., Crawford, Gregory E., West, Anne E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414887/ https://www.ncbi.nlm.nih.gov/pubmed/25849986 http://dx.doi.org/10.1038/nn.3995 |
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