Cargando…

Histomorphometric analysis of microcrack healing after the installation of mini-implants

PURPOSE: The goal of this study was to investigate the histomorphometric characteristics of the healing process of microcracks in the cortical bone after the installation of mini-implants (MIs). METHODS: Self-drilling MIs were inserted into the tibial diaphysis of twelve adult male New Zealand rabbi...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Soobin, Park, Pan-Soo, Baek, Seung-Hak, Yang, Il-Hyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Academy of Periodontology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415003/
https://www.ncbi.nlm.nih.gov/pubmed/25932340
http://dx.doi.org/10.5051/jpis.2015.45.2.62
_version_ 1782369015345184768
author Shin, Soobin
Park, Pan-Soo
Baek, Seung-Hak
Yang, Il-Hyung
author_facet Shin, Soobin
Park, Pan-Soo
Baek, Seung-Hak
Yang, Il-Hyung
author_sort Shin, Soobin
collection PubMed
description PURPOSE: The goal of this study was to investigate the histomorphometric characteristics of the healing process of microcracks in the cortical bone after the installation of mini-implants (MIs). METHODS: Self-drilling MIs were inserted into the tibial diaphysis of twelve adult male New Zealand rabbits. Four MIs per rabbit were placed randomly. The animals were divided into four groups according to the length of the healing period: group A was sacrificed immediately, group B was sacrificed after one week, group C was sacrificed after two weeks, and group D was sacrificed after four weeks. Cortical bone thickness was measured using micro-computed tomography, and histomorphometric analyses of the cumulative length of the microcracks (CLCr) and the total number of microcracks (NCr) were performed using hematoxylin and eosin staining. RESULTS: The microcracks were radially and concentrically aligned in the peri-MI bone. The CLCr decreased significantly one week after the surgery, mainly due to healing of the concentrically aligned microcracks. The CLCr showed another significant decrease from two weeks after the surgery to four weeks after the surgery, mainly reflecting healing of the radially aligned microcracks. A statistically significant decrease in the NCr occurred as the microcracks healed from zero weeks to two weeks. However, no significant difference in the NCr was found between groups C and D. CONCLUSIONS: In order to improve the primary stability of MIs, delayed loading and a healing period of a certain length are recommended to ensure the optimal healing of microcracks and bone remodeling. GRAPHICAL ABSTRACT: [Image: see text]
format Online
Article
Text
id pubmed-4415003
institution National Center for Biotechnology Information
language English
publishDate 2015
publisher Korean Academy of Periodontology
record_format MEDLINE/PubMed
spelling pubmed-44150032015-04-30 Histomorphometric analysis of microcrack healing after the installation of mini-implants Shin, Soobin Park, Pan-Soo Baek, Seung-Hak Yang, Il-Hyung J Periodontal Implant Sci Research Article PURPOSE: The goal of this study was to investigate the histomorphometric characteristics of the healing process of microcracks in the cortical bone after the installation of mini-implants (MIs). METHODS: Self-drilling MIs were inserted into the tibial diaphysis of twelve adult male New Zealand rabbits. Four MIs per rabbit were placed randomly. The animals were divided into four groups according to the length of the healing period: group A was sacrificed immediately, group B was sacrificed after one week, group C was sacrificed after two weeks, and group D was sacrificed after four weeks. Cortical bone thickness was measured using micro-computed tomography, and histomorphometric analyses of the cumulative length of the microcracks (CLCr) and the total number of microcracks (NCr) were performed using hematoxylin and eosin staining. RESULTS: The microcracks were radially and concentrically aligned in the peri-MI bone. The CLCr decreased significantly one week after the surgery, mainly due to healing of the concentrically aligned microcracks. The CLCr showed another significant decrease from two weeks after the surgery to four weeks after the surgery, mainly reflecting healing of the radially aligned microcracks. A statistically significant decrease in the NCr occurred as the microcracks healed from zero weeks to two weeks. However, no significant difference in the NCr was found between groups C and D. CONCLUSIONS: In order to improve the primary stability of MIs, delayed loading and a healing period of a certain length are recommended to ensure the optimal healing of microcracks and bone remodeling. GRAPHICAL ABSTRACT: [Image: see text] Korean Academy of Periodontology 2015-04 2015-04-29 /pmc/articles/PMC4415003/ /pubmed/25932340 http://dx.doi.org/10.5051/jpis.2015.45.2.62 Text en Copyright © 2015 Korean Academy of Periodontology http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0/).
spellingShingle Research Article
Shin, Soobin
Park, Pan-Soo
Baek, Seung-Hak
Yang, Il-Hyung
Histomorphometric analysis of microcrack healing after the installation of mini-implants
title Histomorphometric analysis of microcrack healing after the installation of mini-implants
title_full Histomorphometric analysis of microcrack healing after the installation of mini-implants
title_fullStr Histomorphometric analysis of microcrack healing after the installation of mini-implants
title_full_unstemmed Histomorphometric analysis of microcrack healing after the installation of mini-implants
title_short Histomorphometric analysis of microcrack healing after the installation of mini-implants
title_sort histomorphometric analysis of microcrack healing after the installation of mini-implants
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415003/
https://www.ncbi.nlm.nih.gov/pubmed/25932340
http://dx.doi.org/10.5051/jpis.2015.45.2.62
work_keys_str_mv AT shinsoobin histomorphometricanalysisofmicrocrackhealingaftertheinstallationofminiimplants
AT parkpansoo histomorphometricanalysisofmicrocrackhealingaftertheinstallationofminiimplants
AT baekseunghak histomorphometricanalysisofmicrocrackhealingaftertheinstallationofminiimplants
AT yangilhyung histomorphometricanalysisofmicrocrackhealingaftertheinstallationofminiimplants