Ubiquitin-independent proteosomal degradation of myelin basic protein contributes to development of neurodegenerative autoimmunity

Recent findings indicate that the ubiquitin–proteasome system is involved in the pathogenesis of cancer as well as autoimmune and several neurodegenerative diseases, and is thus a target for novel therapeutics. One disease that is related to aberrant protein degradation is multiple sclerosis, an aut...

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Detalles Bibliográficos
Autores principales: Belogurov, Alexey, Kuzina, Ekaterina, Kudriaeva, Anna, Kononikhin, Alexey, Kovalchuk, Sergey, Surina, Yelena, Smirnov, Ivan, Lomakin, Yakov, Bacheva, Anna, Stepanov, Alexey, Karpova, Yaroslava, Lyupina, Yulia, Kharybin, Oleg, Melamed, Dobroslav, Ponomarenko, Natalia, Sharova, Natalia, Nikolaev, Eugene, Gabibov, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2015
Materias:
Research Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415016/
https://www.ncbi.nlm.nih.gov/pubmed/25634956
http://dx.doi.org/10.1096/fj.14-259333

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