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Molecular Dynamics Simulations of KirBac1.1 Mutants Reveal Global Gating Changes of Kir Channels
[Image: see text] Prokaryotic inwardly rectifying (KirBac) potassium channels are homologous to mammalian Kir channels. Their activity is controlled by dynamical conformational changes that regulate ion flow through a central pore. Understanding the dynamical rearrangements of Kir channels during ga...
Autores principales: | Linder, Tobias, Wang, Shizhen, Zangerl-Plessl, Eva-Maria, Nichols, Colin G., Stary-Weinzinger, Anna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2015
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415035/ https://www.ncbi.nlm.nih.gov/pubmed/25794351 http://dx.doi.org/10.1021/acs.jcim.5b00010 |
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