TLR2 and AP-1/NF-kappaB are involved in the regulation of MMP-9 elicited by heat killed Listeria monocytogenes in human monocytic THP-1 cells

BACKGROUND: MMP-9 is crucial for a normal immune response, but excessive release of this enzyme leads to severe tissue damage. Listeria monocytogenes (LM) is an opportunistic food-borne pathogen causing listerosis, meningitis and sepsis. Heat killed Listeria monocytogenes (HKLM) activates immune sys...

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Detalles Bibliográficos
Autores principales: Shihab, Puthiyaveetil Kochumon, Al-Roub, Areej, Al-Ghanim, Moneera, Al-Mass, Anfal, Behbehani, Kazem, Ahmad, Rasheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415258/
https://www.ncbi.nlm.nih.gov/pubmed/25931987
http://dx.doi.org/10.1186/s12950-015-0077-0

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