Cargando…

Comparative proteomic analysis of hypertrophic chondrocytes in osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a multi-factorial disease leading progressively to loss of articular cartilage and subsequently to loss of joint function. While hypertrophy of chondrocytes is a physiological process implicated in the longitudinal growth of long bones, hypertrophy-like alterations...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tsolis, Konstantinos C, Bei, Ekaterini S, Papathanasiou, Ioanna, Kostopoulou, Fotini, Gkretsi, Vassiliki, Kalantzaki, Kalliopi, Malizos, Konstantinos, Zervakis, Michalis, Tsezou, Aspasia, Economou, Anastassios
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415313/ https://www.ncbi.nlm.nih.gov/pubmed/25945082 http://dx.doi.org/10.1186/s12014-015-9085-6

Ejemplares similares

MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes
por: Kostopoulou, Fotini, et al.
Publicado: (2015)

DNA methylation regulates sclerostin (SOST) expression in osteoarthritic chondrocytes by bone morphogenetic protein 2 (BMP-2) induced changes in Smads binding affinity to the CpG region of SOST promoter
por: Papathanasiou, Ioanna, et al.
Publicado: (2015)

Central Role of SREBP-2 in the Pathogenesis of Osteoarthritis
por: Kostopoulou, Fotini, et al.
Publicado: (2012)

Bone morphogenetic protein-2-induced Wnt/β-catenin signaling pathway activation through enhanced low-density-lipoprotein receptor-related protein 5 catabolic activity contributes to hypertrophy in osteoarthritic chondrocytes
por: Papathanasiou, Ioanna, et al.
Publicado: (2012)

Molecular changes indicative of cartilage degeneration and osteoarthritis development in patients with anterior cruciate ligament injury
por: Papathanasiou, Ioanna, et al.
Publicado: (2016)

Involvement of SOX-9 and FGF-23 in RUNX-2 regulation in osteoarthritic chondrocytes
por: Orfanidou, Timoklia, et al.
Publicado: (2009)

Integration of Transcriptome and MicroRNA Profile Analysis of iMSCs Defines Their Rejuvenated State and Conveys Them into a Novel Resource for Cell Therapy in Osteoarthritis
por: Konteles, Vasileios, et al.
Publicado: (2023)

Integrative MicroRNA and Proteomic Approaches Identify Novel Osteoarthritis Genes and Their Collaborative Metabolic and Inflammatory Networks
por: Iliopoulos, Dimitrios, et al.
Publicado: (2008)

Oxidative Stress Response Is Mediated by Overexpression and Spatiotemporal Regulation of Caveolin-1
por: Goutas, Andreas, et al.
Publicado: (2020)

Dual Role of SIRT1 in Autophagy and Lipid Metabolism Regulation in Osteoarthritic Chondrocytes
por: Papageorgiou, Aliki-Alexandra, et al.
Publicado: (2021)

MicroRNAs and the Diagnosis of Childhood Acute Lymphoblastic Leukemia: Systematic Review, Meta-Analysis and Re-Analysis with Novel Small RNA-Seq Tools
por: Kyriakidis, Ioannis, et al.
Publicado: (2022)

Hypertrophic differentiation of chondrocytes in osteoarthritis: the developmental aspect of degenerative joint disorders
por: Dreier, Rita
Publicado: (2010)

Synergies of Radiomics and Transcriptomics in Lung Cancer Diagnosis: A Pilot Study
por: Dovrou, Aikaterini, et al.
Publicado: (2023)

Recent Insights into the Contribution of the Changing Hypertrophic Chondrocyte Phenotype in the Development and Progression of Osteoarthritis
por: Ripmeester, Ellen G. J., et al.
Publicado: (2018)

Adseverin, an actin-binding protein, modulates hypertrophic chondrocyte differentiation and osteoarthritis progression
por: Chan, Byron, et al.
Publicado: (2023)

Inflammatory and Metabolic Signaling Interfaces of the Hypertrophic and Senescent Chondrocyte Phenotypes Associated with Osteoarthritis
por: Horváth, Emőke, et al.
Publicado: (2023)

Depletion of Ras Suppressor-1 (RSU-1) promotes cell invasion of breast cancer cells through a compensatory upregulation of a truncated isoform
por: Gkretsi, Vasiliki, et al.
Publicado: (2019)

Osteogenic fate of hypertrophic chondrocytes
por: Yang, Guan, et al.
Publicado: (2014)

New Sequence Variants in HLA Class II/III Region Associated with Susceptibility to Knee Osteoarthritis Identified by Genome-Wide Association Study
por: Nakajima, Masahiro, et al.
Publicado: (2010)

Hypertrophic chondrocytes at the junction of musculoskeletal structures
por: Chen, Ning, et al.
Publicado: (2023)

Association of a BMP5 microsatellite with knee osteoarthritis: case-control study
por: Rodriguez-Fontenla, Cristina, et al.
Publicado: (2012)

Gremlin-1 and BMP-4 Overexpressed in Osteoarthritis Drive an Osteochondral-Remodeling Program in Osteoblasts and Hypertrophic Chondrocytes
por: Pérez-Lozano, Maria-Luisa, et al.
Publicado: (2022)

Simulation in Clinical Nursing Education
por: Koukourikos, Konstantinos, et al.
Publicado: (2021)

Hypertrophic chondrocytes undergo further differentiation in culture
Publicado: (1992)

Increased Frequency of Health Anxiety in Health Science Students: a Cross Sectional Study in a Greek University
por: Papadopoulou, Androniki, et al.
Publicado: (2021)

Serum microRNA array analysis identifies miR-140-3p, miR-33b-3p and miR-671-3p as potential osteoarthritis biomarkers involved in metabolic processes
por: Ntoumou, E., et al.
Publicado: (2017)

The Signaling Pathways Involved in Chondrocyte Differentiation and Hypertrophic Differentiation
por: Li, Jianmei, et al.
Publicado: (2016)

Cadherin and Wnt signaling pathways as key regulators in diabetic nephropathy
por: Tziastoudi, Maria, et al.
Publicado: (2021)

Osteoblast-Chondrocyte Interactions in Osteoarthritis
por: Findlay, David M., et al.
Publicado: (2014)

Chondrocyte Apoptosis in the Pathogenesis of Osteoarthritis
por: Hwang, Hyun Sook, et al.
Publicado: (2015)

Chondrocyte death involvement in osteoarthritis
por: Salucci, S., et al.
Publicado: (2022)

Prolonged Application of High Fluid Shear to Chondrocytes Recapitulates Gene Expression Profiles Associated with Osteoarthritis
por: Zhu, Fei, et al.
Publicado: (2010)

Non-coding RNAs in cancer-associated cachexia: clinical implications and future perspectives
por: Kottorou, Anastasia, et al.
Publicado: (2021)

Regulated Production of Mineralization-competent Matrix Vesicles in Hypertrophic Chondrocytes
por: Kirsch, Thorsten, et al.
Publicado: (1997)

Embryological Results of Couples Undergoing ICSI-ET Treatments with Males Carrying the Single Nucleotide Polymorphism rs175080 of the MLH3 Gene
por: Anifandis, George, et al.
Publicado: (2017)

Comprehensive subcellular topologies of polypeptides in Streptomyces
por: Tsolis, Konstantinos C., et al.
Publicado: (2018)

Oxidative stress induces chondrocyte telomere instability and chondrocyte dysfunctions in osteoarthritis
por: Yudoh, K, et al.
Publicado: (2003)

T cell–chondrocyte interaction in the pathogenesis of osteoarthritis
por: Nakamura, H, et al.
Publicado: (2003)

Biomarkers of Chondrocyte Apoptosis and Autophagy in Osteoarthritis
por: Musumeci, Giuseppe, et al.
Publicado: (2015)

Chondrocyte ferroptosis contribute to the progression of osteoarthritis
por: Yao, Xudong, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_o38bfacmodia6h7uv3bouunihp