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Clinical outcome and expression of mutant P53, P16, and Smad4 in lung adenocarcinoma: a prospective study

BACKGROUND: Whole-exome sequencing has shown that lung adenocarcinoma (LAC) can be driven by mutant genes, including TP53, P16, and Smad4. The aim of this study was to clarify protein alterations of P53, P16, and Smad4 and to explore their correlations between the protein alterations and clinical ou...

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Detalles Bibliográficos
Autores principales:	Bian, Chunan, Li, Zhongyou, Xu, Youtao, Wang, Jie, Xu, Lin, Shen, Hongbing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415338/ https://www.ncbi.nlm.nih.gov/pubmed/25890228 http://dx.doi.org/10.1186/s12957-015-0502-0

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