miR-21 and miR-145 cooperation in regulation of colon cancer stem cells

BACKGROUND: Acquired drug resistance is one of the major reasons for failing cancer therapies. Although the reasons are not fully understood, they may be related to the presence of cancer stem cells (CSCs). We have reported that chemo-resistant (CR) colon cancer cells, highly enriched in CSCs, exhib...

Descripción completa

Detalles Bibliográficos
Autores principales: Yu, Yingjie, Nangia-Makker, Pratima, Farhana, Lulu, G. Rajendra, Sindhu, Levi, Edi, Majumdar, Adhip PN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415383/
https://www.ncbi.nlm.nih.gov/pubmed/25928322
http://dx.doi.org/10.1186/s12943-015-0372-7