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Memory CD8(+) T cells colocalize with IL-7(+) stromal cells in bone marrow and rest in terms of proliferation and transcription
It is believed that memory CD8(+) T cells are maintained in secondary lymphoid tissues, peripheral tissues, and BM by homeostatic proliferation. Their survival has been shown to be dependent on IL-7, but it is unclear where they acquire it. Here we show that in murine BM, memory CD8(+) T cells indiv...
Autores principales: | Sercan Alp, Özen, Durlanik, Sibel, Schulz, Daniel, McGrath, Mairi, Grün, Joachim R, Bardua, Marcus, Ikuta, Koichi, Sgouroudis, Evridiki, Riedel, René, Zehentmeier, Sandra, Hauser, Anja E, Tsuneto, Motokazu, Melchers, Fritz, Tokoyoda, Koji, Chang, Hyun-Dong, Thiel, Andreas, Radbruch, Andreas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415462/ https://www.ncbi.nlm.nih.gov/pubmed/25639669 http://dx.doi.org/10.1002/eji.201445295 |
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