TIGAR regulates DNA damage and repair through pentosephosphate pathway and Cdk5-ATM pathway

Previous study revealed that the protective effect of TIGAR in cell survival is mediated through the increase in PPP (pentose phosphate pathway) flux. However, it remains unexplored if TIGAR plays an important role in DNA damage and repair. This study investigated the role of TIGAR in DNA damage res...

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Detalles Bibliográficos
Autores principales: Yu, Hong-Pei, Xie, Jia-Ming, Li, Bin, Sun, Yi-Hui, Gao, Quan-Geng, Ding, Zhi-Hui, Wu, Hao-Rong, Qin, Zheng-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415581/
https://www.ncbi.nlm.nih.gov/pubmed/25928429
http://dx.doi.org/10.1038/srep09853

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415581/
https://www.ncbi.nlm.nih.gov/pubmed/25928429
http://dx.doi.org/10.1038/srep09853

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