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Drug-induced regulatory overcompensation has motivational consequences: Implications for homeostatic and allostatic models of drug addiction
Initial administration of 60% nitrous oxide (N(2)O) at 21°C ambient temperature reduces core temperature (Tc) in rats, but tolerance develops to this hypothermic effect over several administrations. After additional N(2)O administrations, a hyperthermic overcompensation (sign-reversal) develops such...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415621/ https://www.ncbi.nlm.nih.gov/pubmed/25938126 http://dx.doi.org/10.4161/23328940.2014.944802 |