Cargando…

A New Paradigm to Mitigate Osteosarcoma by Regulation of MicroRNAs and Suppression of the NF-κB Signaling Cascade

Osteosarcoma (OS) is one of the most common malignant primary bone tumors and NF-κB appears to play a causative role, but the mechanisms are poorly understood. OS is one of the pleomorphic, highly metastasized and invasive neoplasm which is capable to generate osteoid, osteoclast and osteoblast matr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mongre, Raj Kumar, Sodhi, Simrinder Singh, Ghosh, Mrinmoy, Kim, Jeong Hyun, Kim, Nameun, Sharma, Neelesh, Jeong, Dong Kee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society of Developmental Biology 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415640/ https://www.ncbi.nlm.nih.gov/pubmed/25949190 http://dx.doi.org/10.12717/DR.2014.18.4.197

Ejemplares similares

Epigenetic induction of epithelial to mesenchymal transition by LCN2 mediates metastasis and tumorigenesis, which is abrogated by NF-κB inhibitor BRM270 in a xenograft model of lung adenocarcinoma
por: MONGRE, RAJ KUMAR, et al.
Publicado: (2015)

An integrated in silico approach for functional and structural impact of non- synonymous SNPs in the MYH1 gene in Jeju Native Pigs
por: Ghosh, Mrinmoy, et al.
Publicado: (2016)

An Approach to Identify SNPs in the Gene Encoding Acetyl-CoA Acetyltransferase-2 (ACAT-2) and Their Proposed Role in Metabolic Processes in Pig
por: Sodhi, Simrinder Singh, et al.
Publicado: (2014)

Wogonin suppresses stem cell-like traits of CD133 positive osteosarcoma cell via inhibiting matrix metallopeptidase-9 expression
por: Huynh, Do Luong, et al.
Publicado: (2017)

A PiggyBac mediated approach for lactoferricin gene transfer in bovine mammary epithelial stem cells for management of bovine mastitis
por: Sharma, Neelesh, et al.
Publicado: (2017)

Nanoformulations of curcumin: an emerging paradigm for improved remedial application
por: Gera, Meeta, et al.
Publicado: (2017)

Cascades between miRNAs, lncRNAs and the NF-κB signaling pathway in gastric cancer (Review)
por: Chen, Risheng, et al.
Publicado: (2021)

Applications of Omics Technology for Livestock Selection and Improvement
por: Chakraborty, Dibyendu, et al.
Publicado: (2022)

Growth-inducing effects of argon plasma on soybean sprouts via the regulation of demethylation levels of energy metabolism-related genes
por: Zhang, Jiao Jiao, et al.
Publicado: (2017)

Resveratrol mitigates lipopolysaccharide-mediated acute inflammation in rats by inhibiting the TLR4/NF-κBp65/MAPKs signaling cascade
por: Wang, Guangxi, et al.
Publicado: (2017)

Lethality of inappropriate plasma exposure on chicken embryonic development
por: Zhang, Jiao Jiao, et al.
Publicado: (2017)

BRM270 Inhibits the Proliferation of CD44 Positive Pancreatic Ductal Adenocarcinoma Cells via Downregulation of Sonic Hedgehog Signaling
por: Huynh, Do Luong, et al.
Publicado: (2019)

Activation of Nrf2 by Esculetin Mitigates Inflammatory Responses through Suppression of NF-κB Signaling Cascade in RAW 264.7 Cells
por: Jayakumar, Thanasekaran, et al.
Publicado: (2022)

Expression of NF-κB and PTEN in osteosarcoma and its clinical significance
por: Gong, Teng, et al.
Publicado: (2017)

Functional interplay between long non-coding RNAs and the Wnt signaling cascade in osteosarcoma
por: He, Jieyu, et al.
Publicado: (2021)

Osteosarcoma: Evolution of Treatment Paradigms
por: Jaffe, Norman, et al.
Publicado: (2013)

MicroRNA-7450 regulates non-thermal plasma-induced chicken Sertoli cell apoptosis via adenosine monophosphate-activated protein kinase activation
por: Zhang, Jiao Jiao, et al.
Publicado: (2018)

Metal-Based Nanoparticles and Their Relevant Consequences on Cytotoxicity Cascade and Induced Oxidative Stress
por: Min, Yunhui, et al.
Publicado: (2023)

MicroRNA-128 suppresses paclitaxel-resistant lung cancer by inhibiting MUC1-C and BMI-1 in cancer stem cells
por: Koh, Hyebin, et al.
Publicado: (2017)

β-Myrcene Mitigates Colon Inflammation by Inhibiting MAP Kinase and NF-κB Signaling Pathways
por: Almarzooqi, Saeeda, et al.
Publicado: (2022)

BRM270 inhibits cancer stem cell maintenance via microRNA regulation in chemoresistant A549 lung adenocarcinoma cells
por: Kwon, Taeho, et al.
Publicado: (2018)

Mitigation of cascading failures in complex networks
por: Smolyak, Alex, et al.
Publicado: (2020)

PAK1 modulates a PPARγ/NF-κB cascade in intestinal inflammation
por: Dammann, Kyle, et al.
Publicado: (2015)

Expression of NF-κB associated lncRNAs in schizophrenia
por: Safa, Amin, et al.
Publicado: (2020)

Augmenting NF-κB in poor-risk CLL: A general paradigm for other cancers?
por: Tuveson, David, et al.
Publicado: (2015)

Glycogen Synthase Kinase-3β, NF-κB Signaling, and Tumorigenesis of Human Osteosarcoma
por: Tang, Qing-Lian, et al.
Publicado: (2012)

Bmi-1-targeting suppresses osteosarcoma aggressiveness through the NF-κB signaling pathway
por: Liu, Jiaguo, et al.
Publicado: (2017)

Punicalagin inhibited proliferation, invasion and angiogenesis of osteosarcoma through suppression of NF-κB signaling
por: Huang, Tao, et al.
Publicado: (2020)

Resveratrol is cytotoxic and acts synergistically with NF-κB inhibition in osteosarcoma MG-63 cells
por: Xu, Ning, et al.
Publicado: (2020)

Awareness, knowledge, and risks of zoonotic diseases among livestock farmers in Punjab
por: Hundal, Jaspal Singh, et al.
Publicado: (2016)

The Tumor Suppressor, p53, Negatively Regulates Non-Canonical NF-κB Signaling through miRNA-Induced Silencing of NF-κB–Inducing Kinase
por: Jang, Hanbit, et al.
Publicado: (2020)

Stem Cell Research: A Novel Boulevard towards Improved Bovine Mastitis Management
por: Sharma, Neelesh, et al.
Publicado: (2013)

MicroRNA analysis suggests an additional level of feedback regulation in the NF-κB signaling cascade
por: Mechtler, Peter, et al.
Publicado: (2015)

Haloperidol Instigates Endometrial Carcinogenesis and Cancer Progression by the NF-κB/CSF-1 Signaling Cascade
por: Chiang, Jung-Ying, et al.
Publicado: (2022)

Oleanane-triterpenoids from Panax stipuleanatus inhibit NF-κB
por: Liang, Chun, et al.
Publicado: (2013)

Defining Emerging Roles for NF-κB in Antivirus Responses: Revisiting the Interferon-β Enhanceosome Paradigm
por: Balachandran, Siddharth, et al.
Publicado: (2011)

MicroRNAs Modulate the Dynamics of the NF-κB Signaling Pathway
por: Vaz, Candida, et al.
Publicado: (2011)

NF-κB-regulated, proinflammatory miRNAs in Alzheimer's disease
por: Lukiw, Walter J
Publicado: (2012)

MG53 suppresses NF-κB activation to mitigate age-related heart failure
por: Wang, Xiaoliang, et al.
Publicado: (2021)

Zhuanggu Guanjie herbal formula mitigates osteoarthritis via the NF-κB transduction mechanism
por: Guowei, Gong, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_j762k7oeqo43ucek2gnmej3fbo