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Transcriptional Modulation of Intestinal Innate Defense/Inflammation Genes by Preterm Infant Microbiota in a Humanized Gnotobiotic Mouse Model
BACKGROUND AND AIMS: It is known that postnatal functional maturation of the small intestine is facilitated by microbial colonization of the gut. Preterm infants exhibit defects in gut maturation, weak innate immunity against intestinal infection and increased susceptibility to inflammatory disorder...
Autores principales: | Lu, Lei, Yu, Yueyue, Guo, Yuee, Wang, Yunwei, Chang, Eugene B., Claud, Erika C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415773/ https://www.ncbi.nlm.nih.gov/pubmed/25928420 http://dx.doi.org/10.1371/journal.pone.0124504 |
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