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Phase I Clinical Trial of a Recombinant Blood Stage Vaccine Candidate for Plasmodium falciparum Malaria Based on MSP1 and EBA175

BACKGROUND: A phase I randomised, controlled, single blind, dose escalation trial was conducted to evaluate safety and immunogenicity of JAIVAC-1, a recombinant blood stage vaccine candidate against Plasmodium falciparum malaria, composed of a physical mixture of two recombinant proteins, PfMSP-1(19...

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Detalles Bibliográficos
Autores principales:	Chitnis, Chetan E., Mukherjee, Paushali, Mehta, Shantanu, Yazdani, Syed Shams, Dhawan, Shikha, Shakri, Ahmad Rushdi, Bharadwaj, Rukmini, Gupta, Puneet Kumar, Hans, Dhiraj, Mazumdar, Suman, Singh, Bijender, Kumar, Sanjeev, Pandey, Gaurav, Parulekar, Varsha, Imbault, Nathalie, Shivyogi, Preethi, Godbole, Girish, Mohan, Krishna, Leroy, Odile, Singh, Kavita, Chauhan, Virander S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415778/ https://www.ncbi.nlm.nih.gov/pubmed/25927360 http://dx.doi.org/10.1371/journal.pone.0117820

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