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Functional Characterization of D9, a Novel Deazaneplanocin A (DZNep) Analog, in Targeting Acute Myeloid Leukemia (AML)

Aberrant epigenetic events contribute to tumorigenesis of all human cancers. Significant efforts are underway in developing new generation of epigenetic cancer therapeutics. Although clinical trials for agents targeting DNA hypermethylation and histone deacetylation have yielded promising results, d...

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Detalles Bibliográficos
Autores principales: Jiang, Xia, Lim, Cheryl Zi Hui, Li, Zhimei, Lee, Puay Leng, Yatim, Siti Maryam J. M., Guan, Peiyong, Li, Juntao, Zhou, Jianbiao, Pan, Jingxuan, Chng, Wee-Joo, Chai, Christina L. L., Yu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415792/
https://www.ncbi.nlm.nih.gov/pubmed/25928216
http://dx.doi.org/10.1371/journal.pone.0122983