Heterologous Expression in Remodeled C. elegans: A Platform for Monoaminergic Agonist Identification and Anthelmintic Screening

Monoamines, such as 5-HT and tyramine (TA), paralyze both free-living and parasitic nematodes when applied exogenously and serotonergic agonists have been used to clear Haemonchus contortus infections in vivo. Since nematode cell lines are not available and animal screening options are limited, we h...

Descripción completa

Detalles Bibliográficos
Autores principales: Law, Wenjing, Wuescher, Leah M., Ortega, Amanda, Hapiak, Vera M., Komuniecki, Patricia R., Komuniecki, Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415803/
https://www.ncbi.nlm.nih.gov/pubmed/25928899
http://dx.doi.org/10.1371/journal.ppat.1004794

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415803/
https://www.ncbi.nlm.nih.gov/pubmed/25928899
http://dx.doi.org/10.1371/journal.ppat.1004794

Ejemplares similares