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Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection

Uropathogenic E. coli (UPEC) is the primary cause of urinary tract infections (UTI) affecting approximately 150 million people worldwide. Here, we revealed the importance of transcriptional regulator hypoxia-inducible factor-1 α subunit (HIF-1α) in innate defense against UPEC-mediated UTI. The effec...

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Detalles Bibliográficos
Autores principales:	Lin, Ann E., Beasley, Federico C., Olson, Joshua, Keller, Nadia, Shalwitz, Robert A., Hannan, Thomas J., Hultgren, Scott J., Nizet, Victor
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415805/ https://www.ncbi.nlm.nih.gov/pubmed/25927232 http://dx.doi.org/10.1371/journal.ppat.1004818

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