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Blood Pressure Variation Throughout Pregnancy According to Early Gestational BMI: A Brazilian Cohort
BACKGROUND: The maternal cardiovascular system undergoes progressive adaptations throughout pregnancy, causing blood pressure fluctuations. However, no consensus has been established on its normal variation in uncomplicated pregnancies. OBJECTIVE: To describe the variation in systolic blood pressure...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Sociedade Brasileira de Cardiologia
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415864/ https://www.ncbi.nlm.nih.gov/pubmed/25993591 http://dx.doi.org/10.5935/abc.20150007 |
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author | Rebelo, Fernanda Farias, Dayana Rodrigues Mendes, Roberta Hack Schlüssel, Michael Maia Kac, Gilberto |
author_facet | Rebelo, Fernanda Farias, Dayana Rodrigues Mendes, Roberta Hack Schlüssel, Michael Maia Kac, Gilberto |
author_sort | Rebelo, Fernanda |
collection | PubMed |
description | BACKGROUND: The maternal cardiovascular system undergoes progressive adaptations throughout pregnancy, causing blood pressure fluctuations. However, no consensus has been established on its normal variation in uncomplicated pregnancies. OBJECTIVE: To describe the variation in systolic blood pressure (SBP) and diastolic blood pressure (DBP) levels during pregnancy according to early pregnancy body mass index (BMI). METHODS: SBP and DBP were measured during the first, second and third trimesters and at 30-45 days postpartum in a prospective cohort of 189 women aged 20-40 years. BMI (kg/m(2)) was measured up to the 13(th) gestational week and classified as normal-weight (<25.0) or excessive weight (≥25.0). Longitudinal linear mixed-effects models were used for statistical analysis. RESULTS: A decrease in SBP and DBP was observed from the first to the second trimester (β(SBP)=-0.394; 95%CI: -0.600- -0.188 and β(DBP)=-0.617; 95%CI: -0.780- -0.454), as was an increase in SBP and DBP up to 30-45 postpartum days (β(SBP)=0.010; 95%CI: 0.006-0.014 and β(DBP)=0.015; 95%CI: 0.012-0.018). Women with excessive weight at early pregnancy showed higher mean SBP in all gestational trimesters, and higher mean DBP in the first and third trimesters. Excessive early pregnancy BMI was positively associated with prospective changes in SBP (β(SBP)=7.055; 95%CI: 4.499-9.610) and in DBP (β(DBP)=3.201; 95%CI: 1.136-5.266). CONCLUSION: SBP and DBP decreased from the first to the second trimester and then increased up to the postpartum period. Women with excessive early pregnancy BMI had higher SBP and DBP than their normal-weight counterparts throughout pregnancy, but not in the postpartum period. |
format | Online Article Text |
id | pubmed-4415864 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2015 |
publisher | Sociedade Brasileira de Cardiologia |
record_format | MEDLINE/PubMed |
spelling | pubmed-44158642015-05-04 Blood Pressure Variation Throughout Pregnancy According to Early Gestational BMI: A Brazilian Cohort Rebelo, Fernanda Farias, Dayana Rodrigues Mendes, Roberta Hack Schlüssel, Michael Maia Kac, Gilberto Arq Bras Cardiol Original Articles BACKGROUND: The maternal cardiovascular system undergoes progressive adaptations throughout pregnancy, causing blood pressure fluctuations. However, no consensus has been established on its normal variation in uncomplicated pregnancies. OBJECTIVE: To describe the variation in systolic blood pressure (SBP) and diastolic blood pressure (DBP) levels during pregnancy according to early pregnancy body mass index (BMI). METHODS: SBP and DBP were measured during the first, second and third trimesters and at 30-45 days postpartum in a prospective cohort of 189 women aged 20-40 years. BMI (kg/m(2)) was measured up to the 13(th) gestational week and classified as normal-weight (<25.0) or excessive weight (≥25.0). Longitudinal linear mixed-effects models were used for statistical analysis. RESULTS: A decrease in SBP and DBP was observed from the first to the second trimester (β(SBP)=-0.394; 95%CI: -0.600- -0.188 and β(DBP)=-0.617; 95%CI: -0.780- -0.454), as was an increase in SBP and DBP up to 30-45 postpartum days (β(SBP)=0.010; 95%CI: 0.006-0.014 and β(DBP)=0.015; 95%CI: 0.012-0.018). Women with excessive weight at early pregnancy showed higher mean SBP in all gestational trimesters, and higher mean DBP in the first and third trimesters. Excessive early pregnancy BMI was positively associated with prospective changes in SBP (β(SBP)=7.055; 95%CI: 4.499-9.610) and in DBP (β(DBP)=3.201; 95%CI: 1.136-5.266). CONCLUSION: SBP and DBP decreased from the first to the second trimester and then increased up to the postpartum period. Women with excessive early pregnancy BMI had higher SBP and DBP than their normal-weight counterparts throughout pregnancy, but not in the postpartum period. Sociedade Brasileira de Cardiologia 2015-04 /pmc/articles/PMC4415864/ /pubmed/25993591 http://dx.doi.org/10.5935/abc.20150007 Text en http://creativecommons.org/licenses/by-nc/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Articles Rebelo, Fernanda Farias, Dayana Rodrigues Mendes, Roberta Hack Schlüssel, Michael Maia Kac, Gilberto Blood Pressure Variation Throughout Pregnancy According to Early Gestational BMI: A Brazilian Cohort |
title | Blood Pressure Variation Throughout Pregnancy According to Early
Gestational BMI: A Brazilian Cohort |
title_full | Blood Pressure Variation Throughout Pregnancy According to Early
Gestational BMI: A Brazilian Cohort |
title_fullStr | Blood Pressure Variation Throughout Pregnancy According to Early
Gestational BMI: A Brazilian Cohort |
title_full_unstemmed | Blood Pressure Variation Throughout Pregnancy According to Early
Gestational BMI: A Brazilian Cohort |
title_short | Blood Pressure Variation Throughout Pregnancy According to Early
Gestational BMI: A Brazilian Cohort |
title_sort | blood pressure variation throughout pregnancy according to early
gestational bmi: a brazilian cohort |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415864/ https://www.ncbi.nlm.nih.gov/pubmed/25993591 http://dx.doi.org/10.5935/abc.20150007 |
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