Modeling and study of the mechanism of dilated cardiomyopathy using induced pluripotent stem cells derived from individuals with Duchenne muscular dystrophy

Duchenne muscular dystrophy (DMD) is caused by mutations in the dystrophin gene (DMD), and is characterized by progressive weakness in skeletal and cardiac muscles. Currently, dilated cardiomyopathy due to cardiac muscle loss is one of the major causes of lethality in late-stage DMD patients. To stu...

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Detalles Bibliográficos
Autores principales: Lin, Bo, Li, Yang, Han, Lu, Kaplan, Aaron D., Ao, Ying, Kalra, Spandan, Bett, Glenna C. L., Rasmusson, Randall L., Denning, Chris, Yang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415895/
https://www.ncbi.nlm.nih.gov/pubmed/25791035
http://dx.doi.org/10.1242/dmm.019505

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