A live-cell, high-content imaging survey of 206 endogenous factors across five stress conditions reveals context-dependent survival effects in mouse primary beta cells

AIMS/HYPOTHESIS: Beta cell death is a hallmark of diabetes. It is not known whether specific cellular stresses associated with type 1 or type 2 diabetes require specific factors to protect pancreatic beta cells. No systematic comparison of endogenous soluble factors in the context of multiple pro-ap...

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Detalles Bibliográficos
Autores principales: Yang, Yu Hsuan Carol, Wills, Quin F., Johnson, James D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415993/
https://www.ncbi.nlm.nih.gov/pubmed/25773404
http://dx.doi.org/10.1007/s00125-015-3552-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4415993/
https://www.ncbi.nlm.nih.gov/pubmed/25773404
http://dx.doi.org/10.1007/s00125-015-3552-5

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